High speed particle image velocimetry (HS-PIV) and high speed planar laser induced fluorescence of hydroxyl radical (HS-OH-PLIF) are simultaneously applied to experimentally characterize flame structure, flow topology and a local extinction mechanism in an n-heptane spray jet flame. The experiments also include accurate measurements of droplets size and droplet phase velocity. The lifted stabilized spray flame exhibits a complex shape due to interactions between turbulence, chemistry and droplets. A detailed analysis shows a double flame structure with an inner wrinkled partially premixed and an outer diffusion flame front. Furthermore, an attempt is made to identify the different mechanisms leading to local flame extinctions. In was found that in a canonical spray jet flame configuration, the turbulence scales play a significant role in the dynamic of extinctions. Moreover, due to the presence of large inertial droplets in the outer reaction zone, the reaction rate is disturbed.