Diastereospecific synthesis of new 4-substituted l-theanine derivatives
Résumé
Considering the biological activity of L-theanine as a potent agonist of NMDA receptors, impacting on glutamatergic synapse activity, we have developed an asymmetric synthesis of new enantiomerically pure 4-substituted L-theanine derivatives. The key step is a stereospecific alkylation on a previously synthesized and correctly protected (S)-pyroglutamate.
| Origine | Accord explicite pour ce dépôt |
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