This manifesto advocates for the thoughtful integration of AI in education, emphasising a human-centred approach amid the rapid evolution of artificial intelligence (AI). The chapter explores the transformative potential of large language models (LLM) and generative AI (GenAI) in education, addressing both opportunities and concerns. While AI accelerates change in education, adapting to students’ diverse learning needs, it also poses challenges to traditional assessment paradigms. The manifesto stresses the importance of empowering teachers and students as decision-makers, highlighting the need for a balanced approach to AI integration. It emphasises human-centricity in AI use, promoting ethical considerations, responsible practices, and regulations. The right to choose and co-create is underscored, giving autonomy to educators and learners in selecting technologies aligned with their philosophies. Additionally, the manifesto introduces the concept of hybrid intelligence (HI), advocating collaboration between human and machine intelligence to enhance educational experiences. The manifesto encourages creative uses of AI in education, envisioning a harmonious partnership where AI and humans co-create transformative knowledge.