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Article Dans Une Revue Chemical Communications Année : 2023

Expanding the ‘aplysinospin cascade’ through DNA-templated [2+2] photocycloaddition

Résumé

Inspired by the unique ability of nucleic acids to template chemical transformations that are otherwise impossible in solution, we embarked on the generalisation of our DNA-templated [2+2] photo-induced homo- and heterodimerization of aplysinopsins. Our process ensures a straightforward access to cyclobutane containing natural products and analogues thereof. Most importantly, this conceptual biomimetic achievement presents interesting arguments to build a biosynthetic scenario.

Domaines

Chimie

Dates et versions

hal-04592519 , version 1 (29-05-2024)

Identifiants

Citer

Samuel Oger, Nicolas Duchemin, Yara Mayssa Bendiab, Nicolas Birlirakis, Adam Skiredj, et al.. Expanding the ‘aplysinospin cascade’ through DNA-templated [2+2] photocycloaddition. Chemical Communications, 2023, 59 (28), pp.4221-4224. ⟨10.1039/d3cc00673e⟩. ⟨hal-04592519⟩
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