Burden of the Disease and Management in COVID-19 Hospitalized Patients in MSO and Home Care in France: COVID-Hosp Study (2020-2022) - EPH178 - Archive ouverte HAL Accéder directement au contenu
Communication Dans Un Congrès Année : 2023

Burden of the Disease and Management in COVID-19 Hospitalized Patients in MSO and Home Care in France: COVID-Hosp Study (2020-2022) - EPH178

Résumé

Objectives This study aims to assess the burden of the disease and management in medical, surgical and obstetrics (MSO) and home care (HC) hospitalizations for COVID-19 in France (2020-2022) by patients’ risk status and epidemic waves. Methods This is a retrospective study based on French national hospital database (PMSI). All patients hospitalized for COVID-19 (MSO or HC) were identified between 2020 and 2022. The disease management includes the admissions in intensive care unit (ICU) and the use of mechanical ventilation (MV) during the hospitalization. High-risk patients (HRP) were defined according to the French HTA methodology. Epidemic waves were defined according to the incidence peak observed. Mortality is based on deaths during hospital stays. Results Overall, 800,093 admissions for COVID-19 (97% MSO) and 687,027 patients were recorded. A peak in HC hospitalizations was observed in 2020 (14,117), followed by a decrease of 40% per year. In MSO, the peak occurs in 2021 (300,813), followed by a decrease of 27% in 2022. The average age was 65 (±22) years in MSO and 85 (±13) years in HC. The proportion of hospitalizations of HRP in MSO was between 62% and 78% depending on the year. Conversely, the proportion of HRP remains constant over time in HC, around 95%. The most observed HRP sub-group was the elderly patients (65+). The most important epidemic wave (alpha variant) was observed between March-April 2021 (132,104 hospitalizations). Among MSO hospitalizations 17% were managed in ICU, including 40.3% with MV. The proportions were similar between HRP sub-groups. Death proportion was between 9.7% and 33.1% depending on the disease management and was systematically higher in HRP. Conclusions This study provided a national understanding of the clinical burden of COVID-19 in the French hospital system, which were congested during the crisis. Economic burden and the role of the vaccination remains to be assessed.

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Dates et versions

hal-04512943 , version 1 (20-03-2024)

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M. Pozzar, N Petrica, H. Ben Romdhane, S Fievez, P. Crepey, et al.. Burden of the Disease and Management in COVID-19 Hospitalized Patients in MSO and Home Care in France: COVID-Hosp Study (2020-2022) - EPH178. ISPOR Europe 2023, Nov 2023, Copenhagen, Denmark. ⟨10.1016/j.jval.2023.09.1220⟩. ⟨hal-04512943⟩
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