The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms - Archive ouverte HAL
Article Dans Une Revue Chemical Science Année : 2021

The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms

Mahmudul Hasan
Lotta Happonen
Anders Sundin
Johan Unge
Johan Malmström
Gunilla Westergren-Thorsson
Ulf Ellervik
Anders Malmström
Emil Tykesson

Résumé

Structural studies of human DS-epi1 suggests a new catalytic isomerization mechanism and reveals remarkable similarities to bacterial proteins.
Fichier principal
Vignette du fichier
hkhchemicalsc.pdf (2.05 Mo) Télécharger le fichier
Origine Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-04429650 , version 1 (17-09-2024)

Identifiants

Citer

Mahmudul Hasan, Hamed Khakzad, Lotta Happonen, Anders Sundin, Johan Unge, et al.. The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms. Chemical Science, 2021, 12 (5), pp.1869-1885. ⟨10.1039/D0SC05971D⟩. ⟨hal-04429650⟩
13 Consultations
2 Téléchargements

Altmetric

Partager

More