ASO Visual Abstract: Feasibility and Safety of Oxaliplatin-Based Pressurized Intraperitoneal Aerosol Chemotherapy with or Without Intraoperative Intravenous 5-Fluorouracil and Leucovorin for Colorectal Peritoneal Metastases: A Multicenter Comparative Cohort Study - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Annals of Surgical Oncology Année : 2022

ASO Visual Abstract: Feasibility and Safety of Oxaliplatin-Based Pressurized Intraperitoneal Aerosol Chemotherapy with or Without Intraoperative Intravenous 5-Fluorouracil and Leucovorin for Colorectal Peritoneal Metastases: A Multicenter Comparative Cohort Study

This study (https://doi.org/10.1245/s10434-022-11577- 2) included consecutive patients with histologically proven unresectable and isolated colorectal peritoneal metastases (cPM), treated with PIPAC-Ox in seven tertiary referral centers between January 2015 and April 2020. Toxicity events and oncological outcomes (histological response, progression-free survival, and overall survival) were compared between patients who received intraoperative intravenous 5-FU/L (PIPAC-Ox ? 5-FU/L group) and patients who did not (PIPAC-Ox group). The safety and feasibility of PIPAC-Ox ? 5-FU/L appear to be similar to the safety and feasibility of PIPAC-Ox alone in patients with unresectable cPM. Oncological outcomes must be evaluated in larger studies

Abdelkader Taibi
Olivia Sgarbura
  • Fonction : Auteur
Martin Hübner
  • Fonction : Auteur
Sylvia M Bardet
Mohammed Alyami
  • Fonction : Auteur
Naoual Bakrin
  • Fonction : Auteur
Sylvaine Durand Fontanier
  • Fonction : Auteur
Clarisse Eveno
  • Fonction : Auteur
Johan Gagniere
  • Fonction : Auteur
Basile Pache
  • Fonction : Auteur
Marc Pocard
  • Fonction : Auteur
François Quenet
  • Fonction : Auteur
Hugo Teixeira Farinha
  • Fonction : Auteur
Emilie Thibaudeau
  • Fonction : Auteur
Frederic Dumont
  • Fonction : Auteur
Olivier Glehen
  • Fonction : Auteur

Domaines

Cancer
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Dates et versions

hal-04413344 , version 1 (23-01-2024)

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Abdelkader Taibi, Olivia Sgarbura, Martin Hübner, Sylvia M Bardet, Mohammed Alyami, et al.. ASO Visual Abstract: Feasibility and Safety of Oxaliplatin-Based Pressurized Intraperitoneal Aerosol Chemotherapy with or Without Intraoperative Intravenous 5-Fluorouracil and Leucovorin for Colorectal Peritoneal Metastases: A Multicenter Comparative Cohort Study. Annals of Surgical Oncology, 2022, 29 (8), pp.5254-5255. ⟨10.1245/s10434-022-11675-1⟩. ⟨hal-04413344⟩

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