Mouse models of diabetes-related ulcers: a systematic review and network meta-analysis - Archive ouverte HAL
Article Dans Une Revue EBioMedicine Année : 2023

Mouse models of diabetes-related ulcers: a systematic review and network meta-analysis

Jean-Luc Cracowski
Dominique Sigaudo-Roussel
Charles Khouri

Résumé

Background Diabetic foot ulcers (DFUs) are a common complication of diabetes, associated with important morbidity. Appropriate animal models of DFUs may improve drug development, and subsequently the success rate of clinical trials. However, while many models have been proposed, they are extremely heterogeneous, and no standard has emerged. We thus propose a systematic review with a network meta-analysis (NMA) to gather direct and indirect evidence, and compare the different mouse models of diabetes-related ulcers.
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hal-04278766 , version 1 (23-10-2024)

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Axel Couturier, Clément Calissi, Jean-Luc Cracowski, Dominique Sigaudo-Roussel, Charles Khouri, et al.. Mouse models of diabetes-related ulcers: a systematic review and network meta-analysis. EBioMedicine, 2023, 98, pp.104856. ⟨10.1016/j.ebiom.2023.104856⟩. ⟨hal-04278766⟩

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