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Article Dans Une Revue International Journal of Molecular Sciences Année : 2023

Rejuvenating the Activity of Usual Antibiotics on Resistant Gram-Negative Bacteria: Recent Issues and Perspectives

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Antibiotic resistance continues to evolve and spread beyond all boundaries, resulting in an increase in morbidity and mortality for non-curable infectious diseases. Due to the failure of conventional antimicrobial therapy and the lack of introduction of a novel class of antibiotics, novel strategies have recently emerged to combat these multidrug-resistant infectious microorganisms. In this review, we highlight the development of effective antibiotic combinations and of antibiotics with non-antibiotic activity-enhancing compounds to address the widespread emergence of antibiotic-resistant strains.
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hal-04244602 , version 1 (19-10-2023)

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Jinane Tabcheh, Julia Vergalli, Anne Davin-Régli, Noha Ghanem, Jean-Marie Pages, et al.. Rejuvenating the Activity of Usual Antibiotics on Resistant Gram-Negative Bacteria: Recent Issues and Perspectives. International Journal of Molecular Sciences, 2023, 24 (2), pp.1515. ⟨10.3390/ijms24021515⟩. ⟨hal-04244602⟩

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