Hyaluronate-alginate combination for the preparation of new biomaterials: investigation of the behaviour in aqueous solutions - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue (Article De Synthèse) Biochimica et Biophysica Acta (BBA) - General Subjects Année : 1999

Hyaluronate-alginate combination for the preparation of new biomaterials: investigation of the behaviour in aqueous solutions

Résumé

With the aim of producing a biomaterial for surgical applications, the alginate-hyaluronate association has been investigated. Crossed techniques were used to assess the existence of polymer interactions in aqueous solutions up to 20 mg/ml. Alginate was obtained from algae and hyaluronate was purified from rooster comb. Viscometry measurements using the capillary technique or the Couette flow, together with circular dichroism investigations, evidenced the moderate significance of interactions between the two polysaccharides in dilute solutions. In addition, the case of more concentrated solutions and containing 20 mg/ml alginate was approached by rheological measurements in the flow mode; the behaviour of the polymer associations appeared as a compromise between those of individual polysaccharides.

Dates et versions

hal-04191024 , version 1 (30-08-2023)

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Citer

Sandra Oerther, Elisabeth Payan, François Lapicque, Nathalie Presle, Patrick Hubert, et al.. Hyaluronate-alginate combination for the preparation of new biomaterials: investigation of the behaviour in aqueous solutions. Biochimica et Biophysica Acta (BBA) - General Subjects, 1999, 1426 (1), pp.185-194. ⟨10.1016/s0304-4165(98)00155-x⟩. ⟨hal-04191024⟩
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