Article Dans Une Revue Psychological Medicine Année : 2002

Prevention and treatment of post-partum depression: a controlled randomized study on women at risk

Résumé

Background. Research is needed to evaluate the efficacy of prevention and treatment for post-partum depression. Method. Subjects were screened with the Edinburgh Post-natal Depression Scale (EPDS) at the obstetric clinic. Mothers at risk ( N = 258) (EPDS scores [ges ]9) were randomly assigned to a prevention/treatment group or a control group. The prevention group received one cognitive-behavioural prevention session during hospitalization. At 4 to 6 weeks post-partum, subjects were screened again with the EPDS, after drop-out rates (refusals plus no return of the second EPDS) of 25.4% (33/130) in the intervention group and 10.9% (14/128) in the control group. Mothers with probable depression (EPDS scores [ges ]11) were assessed using the Hamilton Depression Rating Scale (HDRS) and the Beck Depression Inventory (BDI). Mothers with major depression continued in the treatment group ( N = 18) or in the control group ( N = 30). Treated subjects received a cognitive-behavioural programme of between five and eight weekly home-visits. Results. Compared with the control group, women in the prevention group had significant reductions in the frequency of probable depression (30.2% v. 48.2%). Recovery rates based on HDRS scores of <7 and BDI scores of <4 were also significantly greater in the treated group than in the control group. Conclusions. The study suggests that this programme for prevention and treatment of post-partum depression is reasonably well-accepted and efficacious.

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Dates et versions

hal-04147621 , version 1 (30-06-2023)

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Henri Chabrol, Frederique Teissedre, Michèle Saint-Jean, Nathalie Teisseyre, Bernadette Rogé, et al.. Prevention and treatment of post-partum depression: a controlled randomized study on women at risk. Psychological Medicine, 2002, 32 (6), pp.1039-1047. ⟨10.1017/s0033291702006062⟩. ⟨hal-04147621⟩
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