Molecular and Functional Properties of Acid-Sensing Ion Channels
Résumé
Acid-sensing ion channels (ASICs) are voltage-independent H-gated cation channels largely expressed in the nervous system of rodents and humans, and involved in pain sensing and associated pathologies. At least six isoforms (ASIC1a, 1b, 2a, 2b, 3 and 4) associate into homotrimers or heterotrimers to form functional channels with highly pH-dependent gating properties.
Domaines
Sciences du Vivant [q-bio]
Fichier principal
22 - Encyclopedia - molecular-and-functional-properties-of-acid-sensing-ion-channels.pdf (2.71 Mo)
Télécharger le fichier
Origine | Fichiers produits par l'(les) auteur(s) |
---|