From 1535 to 1536, Jacques Cartier undertook his second expedition to North America with the blessings of King Francis I of France. During the winter of his voyage, many members of his crew contracted a serious illness. They were cured by an indigenous medicine shared with them by Domagaya, son of Donnacona, the Iroquois chief with whom they had commerce. Stunned by the power of this therapeutic plant, Annedda, Jacques Cartier decided to return to France with it and to arouse the king's interest. This endeavour failed and, in less than a generation, the plant became unidentifiable in the king's garden of Fontainebleau. Far from adopting an indigenous perspective on plants and medicine, the French captain viewed the plant as a commodity with economic value. Likewise, the Canadian forest in which Annedda grew was seen less as an ecosystem and more as a reservoir of future profits.