Bird fancier's lung serodiagnosis by automated r-IgLL1 ELISA - Archive ouverte HAL
Article Dans Une Revue Journal of Immunological Methods Année : 2022

Bird fancier's lung serodiagnosis by automated r-IgLL1 ELISA

Bird fancier's lung serodiagnosis by automated r-IgLL1 ELISA.

Résumé

Bird fancier's lung (BFL) is the most prevalent form of hypersensitivity pneumonitis (HP) worldwide. The current techniques used for the serological diagnosis of BFL all use crude extracts from feathers, droppings, and blooms as test antigens, which is associated with a lack of standardization and variability of the results. An antigenic protein, immunoglobulin lambda-like polypeptide-1 (IgLL1), isolated from pigeon droppings, was recently identified to be associated with BFL. We used genetic engineering to produce IgLL1 as a recombinant antigen.
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hal-03713088 , version 1 (22-07-2024)

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Adeline Rouzet, Emeline Scherer, Coralie Barrera, Anne Gondouin, Gabriel Reboux, et al.. Bird fancier's lung serodiagnosis by automated r-IgLL1 ELISA. Journal of Immunological Methods, 2022, 505, pp.113267. ⟨10.1016/j.jim.2022.113267⟩. ⟨hal-03713088⟩
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