Bayesian positive source separation (BPSS) is a useful unsupervised approach for hyperspectral data unmixing, where numerical nonnegativity of spectra and abundances has to be ensured, such as in remote sensing. Moreover, it is sensible to impose a sum-to-one (full additivity) constraint to the estimated source abundances in each pixel. Even though nonnegativity and full additivity are two necessary properties to get physically interpretable results, the use of BPSS algorithms has so far been limited by high computation time and large memory requirements due to the Markov chain Monte Carlo calculations. An implementation strategy that allows one to apply these algorithms on a full hyperspectral image, as it is typical in earth and planetary science, is introduced. The effects of pixel selection and the impact of such sampling on the relevance of the estimated component spectra and abundance maps, as well as on the computation times, are discussed. For that purpose, two different data sets have been used: a synthetic one and a real hyperspectral image from Mars.