Service-Oriented Computing (SOC) and SOC systems have been invented, studied, and developed in response to the problems generated by heterogeneity and poor latency, and a need for modularization and standardization. Wide application of SOC, practically in all areas of human endeavors, interconnectivity provided by wireless networks, huge volumes and diversity of data, increased frequency of security attacks, and reliability expectations have increased research, development, and deployment of SOC systems. These circumstances and requirements could only be dealt with by a future generation of SOC systems. This implies a need for fast and high-quality research and wide and efficient dissemination of achieved innovative results. Therefore, a Special Issue (SI) was proposed, and its relevant scope defined. This SI involves a set of high-quality and cross-community scientific papers from various disciplines (e.g., cloud computing, edge computing, business process management). The accepted papers focus on research leading toward future generation of service-oriented computing systems (e.g., dynamic quality of service management in fog computing, time-aware resources allocation in cloud computing, resilient composition in the Internet of Things) with emphasis on advanced results that solve open research problems and have significant impact on the field of service-oriented computing.