Great Efficiency of Nucleosides as Organizing Tools - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Croatica Chemica Acta - izd. tromjesečno Hrvatsko kemijsko društvo Année : 2017

Great Efficiency of Nucleosides as Organizing Tools

Résumé

Bis-porphyrins with flexible linkers such as uridine or 2'-deoxyuridin pre-organize in a face-to-face conformation and form stable sandwich complexes with bidentate base such as DABCO. The gain in stability can be even greater when a dinucleotide linker is used. Such preorganization increases the association constant by one to two orders of magnitude when compared to the one of DABCO with a reference porphyrin. Comparison with rigid tweezers shows a better efficiency of nucleosidic dimers. The choice of rigid spacers is not the only way to pre-organize bis-porphyrins, and well-chosen nucleosidic linkers offer an interesting option for the synthesis of such devices.

Domaines

Chimie
Fichier principal
Vignette du fichier
Croatica Chemica Acta Solladie.pdf (5.63 Mo) Télécharger le fichier
Origine Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-03059672 , version 1 (12-12-2020)

Identifiants

Citer

Sonja Merkaš, Souhaila Bouatra, Régis Rein, Ivo Piantanida, Mladen Žinić, et al.. Great Efficiency of Nucleosides as Organizing Tools. Croatica Chemica Acta - izd. tromjesečno Hrvatsko kemijsko društvo, 2017, 90 (4), ⟨10.5562/cca3247⟩. ⟨hal-03059672⟩
26 Consultations
22 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More