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Article Dans Une Revue Croatica Chemica Acta - izd. tromjesečno Hrvatsko kemijsko društvo Année : 2017

Great Efficiency of Nucleosides as Organizing Tools

Résumé

Bis-porphyrins with flexible linkers such as uridine or 2'-deoxyuridin pre-organize in a face-to-face conformation and form stable sandwich complexes with bidentate base such as DABCO. The gain in stability can be even greater when a dinucleotide linker is used. Such preorganization increases the association constant by one to two orders of magnitude when compared to the one of DABCO with a reference porphyrin. Comparison with rigid tweezers shows a better efficiency of nucleosidic dimers. The choice of rigid spacers is not the only way to pre-organize bis-porphyrins, and well-chosen nucleosidic linkers offer an interesting option for the synthesis of such devices.

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Chimie
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hal-03059672 , version 1 (12-12-2020)

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Sonja Merkaš, Souhaila Bouatra, Régis Rein, Ivo Piantanida, Mladen Žinić, et al.. Great Efficiency of Nucleosides as Organizing Tools. Croatica Chemica Acta - izd. tromjesečno Hrvatsko kemijsko društvo, 2017, 90 (4), ⟨10.5562/cca3247⟩. ⟨hal-03059672⟩
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