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Communication Dans Un Congrès Année : 2015

Glucose-insulin system based on minimal model: A realistic approach

Résumé

This paper presents a new approach to represent the glucose and insulin levels on patients with diabetes type 1 based on the well-known minimal model. In this work a new mathematical model is proposed which attempts modeling properly the malfunction of the pancreas. The model takes into account both: the description of the glucose level in the subcutaneous layer and a meal disturbance term. Further, also has an additional term that represents the insulin in a more realistic approach. In silico simulations are used for first evaluations of the proposed model effectiveness, considering variations on quantity of meals and of insulin supplied.
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Dates et versions

hal-03032108 , version 1 (30-11-2020)

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Adriana Aguilera Gonzalez, Holger Voos, Mohamed Darouach. Glucose-insulin system based on minimal model: A realistic approach. 17th UKSim-AMSS International Conference on Modelling and Simulation, UKSim 2015, Mar 2015, Cambridge, United Kingdom. ⟨10.1109/UKSim.2015.65⟩. ⟨hal-03032108⟩
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