This paper presents the results of functionally graded Ti6Al4V-Mo alloy manufactured with directed energy deposition called CLAD ® (Construction Laser Additive Direct) process. Single track width sample with five gradients of composition, from 0 to 100 wt.% Mo, was manufactured using a coaxial nozzle. Both Ti6Al4V and Mo ratios were modified with a 25 wt.% increase or decrease in the chemical composition of each gradient. A two-powder feeder was used to input the correct ratio of each powder, so as to obtain the desired chemical composition. XRD analysis allowed to define the phases present in each deposition, as well as the lattice parameter. SEM observations showed microstructural evolution from 25 wt% Mo on, namely where the ␤-phase becomes dominant. Moreover, dendrites appear from 50 wt.% Mo on. Microhardness analysis revealed variation along the deposition depending on the chemical composition. The homogeneity of the powder mixture under laser beam was highlighted thanks to tomography on the manufactured samples, which validates the processability of functionally graded material (FGM) by CLAD ® process.