This contribution provides an overview of the SINAPS@ French research project and its main achievements. SINAPS@ stands for ''Earthquake and Nuclear Facility: Improving and Sustaining Safety'', and it has gathered the broad research community together to propose an innovative seismic safety analysis for nuclear facilities. This five-year project was funded by the French government after the 2011 Japanese Tohoku large earthquake and associated tsunami that caused a major accident at the Fukushima Daı¨chiDaı¨chi nuclear power plant. Soon after this disaster, the international community involved in nuclear safety questioned the current methodologies used to define and to account for seismic loadings for nuclear facilities during the design and periodic assessment review phases. Within this framework, worldwide nuclear authorities asked nuclear licensees to perform 'stress tests' to estimate the capacity of their existing facilities for sustaining extreme seismic motions. As an introduction, the French nuclear regulatory framework is presented here, to emphasize the key issues and the scientific challenges. An analysis of the current French practices and the need to better assess the seismic margin of nuclear facilities contributed to the shaping of the scientific road-map of SINAPS@. SINAPS@ was aimed at conducting a continuous analysis of completeness and gaps in databases (for all data types, including geology, seismology, site characterization, materials), of reliability or deficiency of models available to describe physical phenomena (i.e., prediction of seismic motion, site effects, soil and structure interactions, linear and nonlinear wave propagation, material constitutive laws in the nonlinear domain for structural analysis), and of the relevance or weakness of methodologies used for seismic safety assessment. This critical analysis that confronts the methods (either deterministic or prob-abilistic) and the available data in terms of the international state of the art systematically addresses the uncertainty issues. We present the key results achieved in SINAPS@ at each step of the full seismic analysis, with a focus on uncertainty identification, quantification, and propagation. The main lessons learned from SINAPS@ are highlighted. SINAPS@ promotes an innovative integrated approach that is consistent with Guidelines #22, as recently published by the French Nuclear Safety Authority (Guidelines ASN #22 2017), and opens the perspectives to improve current French practice.