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Article Dans Une Revue Chemistry - A European Journal Année : 1999

High Relaxivity for Monomeric Gd(DOTA)-Based MRI Contrast Agents, Thanks to Micellar Self-Organization

João André
  • Fonction : Auteur
Holger Fischer
  • Fonction : Auteur
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Anna Seelig
  • Fonction : Auteur
Helmut Mäcke
  • Fonction : Auteur
André André
  • Fonction : Auteur

Résumé

A new amphiphilic GdIII chelate, which is capable of forming micelles in aqueous solution (see diagram), has been synthesized. Due to this self‐aggregation, the compound has a long rotational correlation time and, consequently, has high proton relaxivities that thus far have only been obtained with macromolecular complexes.

Dates et versions

hal-02080899 , version 1 (27-03-2019)

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Citer

João André, Éva Tóth, Holger Fischer, Anna Seelig, Helmut Mäcke, et al.. High Relaxivity for Monomeric Gd(DOTA)-Based MRI Contrast Agents, Thanks to Micellar Self-Organization. Chemistry - A European Journal, 1999, 5 (10), pp.2977-2983. ⟨10.1002/(SICI)1521-3765(19991001)5:10<2977::AID-CHEM2977>3.0.CO;2-T⟩. ⟨hal-02080899⟩
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