No Discrete Start/Stop Signals in the Dorsal Striatum of Mice Performing a Learned Action
Résumé
Highlights d The striatum represents movement dynamics during performance of a run-and-stop task d Neurons could not be divided into discrete functional groups (start, maintain, and stop) d Striatal spiking activity correlated with running speed on a trial-by-trial basis d Striatal activity is also modulated by non-locomotor movements, such as licking In Brief It has been proposed that the striatum contributes to the execution of learned actions by generating start, maintain, and stop signals. Sales-Carbonell et al. show, in mice performing a run-and-stop task, that such discrete signals cannot be isolated statistically. Rather, the striatum continuously monitors the movement dynamics associated with task performance.
Domaines
Neurobiologie
Origine : Fichiers produits par l'(les) auteur(s)
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