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Article Dans Une Revue Current Biology - CB Année : 2018

No Discrete Start/Stop Signals in the Dorsal Striatum of Mice Performing a Learned Action

Résumé

Highlights d The striatum represents movement dynamics during performance of a run-and-stop task d Neurons could not be divided into discrete functional groups (start, maintain, and stop) d Striatal spiking activity correlated with running speed on a trial-by-trial basis d Striatal activity is also modulated by non-locomotor movements, such as licking In Brief It has been proposed that the striatum contributes to the execution of learned actions by generating start, maintain, and stop signals. Sales-Carbonell et al. show, in mice performing a run-and-stop task, that such discrete signals cannot be isolated statistically. Rather, the striatum continuously monitors the movement dynamics associated with task performance.

Domaines

Neurobiologie
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Dates et versions

hal-01923485 , version 1 (18-01-2019)

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Citer

Carola Sales-Carbonell, Wahiba Taouali, Loubna Khalki, Matthieu Pasquet, Ludovic Petit, et al.. No Discrete Start/Stop Signals in the Dorsal Striatum of Mice Performing a Learned Action. Current Biology - CB, 2018, 28 (19), pp.3044 - 3055.e5. ⟨10.1016/j.cub.2018.07.038⟩. ⟨hal-01923485⟩
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