In this paper we study the problem of parametric inference for multidimensional diffusions based on observations at random stopping times. We work in the asymptotic framework of high frequency data over a fixed horizon. Previous works on the subject (such as [Doh87, GJ93, Gob01, AM04] among others) consider only deterministic, strongly predictable or random, independent of the process, observation times, and do not cover our setting. Under mild assumptions we construct a consistent sequence of estimators, for a large class of stopping time observation grids (studied in [GL14, GS18]). Further we carry out the asymptotic analysis of the estimation error and establish a Central Limit Theorem (CLT) with a mixed Gaussian limit. In addition, in the case of a 1-dimensional parameter, for any sequence of estimators verifying CLT conditions without bias, we prove a uniform a.s. lower bound on the asymptotic variance, and show that this bound is sharp.