We report new mapping, tectonic, metamorphic and U–Pb zircon dating data on the polyphased Tachakoucht–Iriri and Tourtit arc-related units within the Moroccan Pan-African belt (Sirwa window, Anti-Atlas). The studied area contains four different sub-units, from south to north: (1) the Tachakoucht gneisses intruded to its northern part by (2) Iriri intrusions. To the north, the Tachakoucht–Iriri massif is thrusted by (3) the south-verging 760 Ma Khzama ophiolitic sequence intruded by (4) the Tourtit meta-granitic complex. The Tachakoucht gneiss represents former andesitic to dacitic porphyritic rocks crystallized around 740–720 Ma in an intra-oceanic arc setting (IOAS). Subsequently, it has been buried and metamorphosed to 700 °C, 8 kbar in response to early accretion of the arc onto the West African Craton (WAC). This tectono-metamorphic event also led to the dismembering and stacking of back-arc ophiolite onto the arc unit. Subsequently, the Iriri intrusions, a suite of hydrous mafic dykes (hornblende gabbro and fine-grained basalt) and ultramafic (hornblendite) plutons showing subduction zone affinities, intruded the Tachakoucht gneiss under P–T conditions of 750–800 °C and 2–5 kbar. Emplacement of Iriri intrusions led locally to pronounced partial melting of the Tachakoucht gneiss and to the production of leucogranitic melts. These melts crop out into the Iriri–Tachakoucht gneiss contacts as leucogneissic bands (former leucosomes, dated at 651 ± 5 Ma) but also intruded the Khzama ophiolite to form the Tourtit granite (dated at 651 ± 3 Ma). These ages (651–641 Ma) also constrain the timing of Iriri intrusion emplacement. The entire complex has been overprinted by a second deformation event under greenschist to amphibolite facies conditions marked by transposition of primary structures and a development of mylonitic shear zones. These results and those published on the Bou Azzer window show that two phases of subduction-related magmatism occurred in the Anti-Atlas belt and that they were separated by an early accretion of the intra-oceanic arc system (IOAS) onto the West African craton passive margin. Our interpretations also validate thermo-mechanical models predicting an intense perturbation of subduction dynamics during arc-continent collision (i.e. composite subductions, polarity reversal) which can expand the production of typical hydrous arc magma and induces a late magmatic phase after partial or total accretion of the IOAS.