For a fluid-solid interaction problem with Lipschitz interface, we investigate the partial Fréchet differentiability of the solutions and the approximate far-field-pattern with respect to solid material parameters. Differentiability is shown in standard Sobolev framework, and the derivatives are characterized as solutions to inhomogeneous fluid-solid transmission problems. To validate the accuracy of the characterization, we compare analytical values with numerical ones given by Interior Penalty Discontinuous Galerkin (IPDG) in a setting with circular obstacles. Our comparisons also show that IPDG gives results with high precision and incurs almost no effect of discretization error accumulation.