Improvements on the distribution of maximal segmental scores in a Markovian sequence - Archive ouverte HAL
Pré-Publication, Document De Travail Année : 2018

Improvements on the distribution of maximal segmental scores in a Markovian sequence

Résumé

Let A_i, i≥0 be a finite state irreducible aperiodic Markov chain and f a lattice score function such that the average score is negative and positive scores are possible. Define S_0 := 0 and S_k := f(A_1) +...+ f(A_k) the successive partial sums, S^+ the maximal non-negative partial sum, Q_1 the maximal segmental score of the first non-negative excursion and M_n := max (S_k − S_j: 0≤j≤k≤n) the local score first defined by Karlin and Altschul (1990). We establish recursive formulae for the exact distribution of S^+ and derive new approximations for the distributions of Q_1 and M_n. Computational methods are presented in a simple application case and comparison is performed between these new approximations and the ones proposed by Karlin and Dembo (1992) in order to evaluate improvements.
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Dates et versions

hal-01726031 , version 1 (07-03-2018)
hal-01726031 , version 2 (24-09-2019)

Identifiants

  • HAL Id : hal-01726031 , version 1

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Simona Grusea, Sabine Mercier. Improvements on the distribution of maximal segmental scores in a Markovian sequence. 2018. ⟨hal-01726031v1⟩
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