Overview on inverse problem solving techniques to estimate optical properties from fibered spectroscopic devices
Résumé
This course is an overview presentation of main approaches to estimate the optical properties of biological tissues from fibered optical spectroscopy measurements and requiring inverse problem solving.
First, the principle of “tissular optical biopsy” will be considered including instrumentation configuration (sources, detectors, multi-fiber optical probe geometry), light-tissue photo-physical interactions in the UV-Visible wavelength range and medical applications.
Second, the generic problem of tissue optical parameters estimation (inverse problem solving) in the above mentioned configuration will be expressed and challenges in terms of modelling, forward problem simulation, cost-function and optimization methods will be presented.
Third, state-of-the art solutions and results as well as latest and perspective development will be overviewed.