EvoKEN: evolutionary knowledge extraction in networks
Résumé
We introduce a multi-factorial, multi-level approach to build and explore evolutionary scenarios of complex protein networks. EvoKEN combines a unique formalism for integrating multiple types of data associated with network molecular components and knowledge extraction techniques for detecting cohesive/anomalous evolutionary processes. We analyzed known human pathway maps and identified perturbations or specializations at the local topology level that reveal important evolutionary and functional aspects of these cellular systems.
| Origine | Fichiers produits par l'(les) auteur(s) |
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