Within the current economic context, enterprises are facing new interoperability issues due to increasing needs of eBusiness Collaboration within the emerging digital ecosystems they belong to. They also need to be able to keep in pace with their heterogeneous internal legacy systems. In addition, they should not have to modify their infrastructure or applications for fast and short collaboration implying information and knowledge interchange with new partners of their ecosystem. Current solutions are less and less adapted to face increasing needs and complexity. As proposing a new disruptive approach and technologies is inappropriate, this paper presents how to build enterprise application interoperability framework based on simultaneous and coherent usage of eBusiness standards used by a given ecosystem, combining usage of the different relevant frameworks supporting these standards. The goal is achievement of "pragmatic" interoperability. For the proposed approach, we consider simultaneous usage of Model Driven Engineering, Enterprise Modeling and Service Oriented Architecture. We also promote systematic usage of commodities on the WEB based on open and governed standards. Doing so, we have to solve issues related to semantic preservation, all along the lifecycle of the artifacts and infrastructures required to define and exploit an application. We introduce for that the concept of Extended Hypermodels and associated grounds.