This paper deals with global sensitivity analysis of computer model output. Given a set of independent input sample and associated model output vector with possibly the vector of output derivatives with respect to the input variables , we show that it is possible to evaluate the following global sensitivity measures: (i) the Sobol' indices, (ii) the Borgonovo's density-based sensitivity measure, and (iii) the derivative-based global sensitivity measure of Sobol' and Kucherenko. We compare the efficiency of the different methods to address factors fixing setting, an important issue in global sensitivity analysis. First, global sensitivity analysis of the Ishigami function is performed with the different methods. Then, they are applied to two different responses of a soil drainage model. The results show that the polynomial chaos expansion for estimating Sobol' indices is the most efficient approach.