Surveillance and management of Echinococcus multilocularis in a wildlife park.
Gérald Umhang
(1)
,
Jennifer Lahoreau
,
Vanessa Hormaz
,
Jean-Marc Boucher
(2)
,
Amandine Guenon
,
Damien Montange
(3)
,
Frédéric Grenouillet
(3)
,
Franck Boue
Gérald Umhang
- Fonction : Auteur
- PersonId : 884916
- ORCID : 0000-0001-6944-7474
- IdRef : 22553262X
Jennifer Lahoreau
- Fonction : Auteur
Vanessa Hormaz
- Fonction : Auteur
Amandine Guenon
- Fonction : Auteur
Frédéric Grenouillet
- Fonction : Auteur
- PersonId : 16667
- IdHAL : frederic-grenouillet
- ORCID : 0000-0001-6001-3135
- IdRef : 059337567
Franck Boue
- Fonction : Auteur
- PersonId : 879860
- ORCID : 0000-0003-0957-1320
- IdRef : 095056319
Résumé
The fox tapeworm Echinococcus multilocularis is the causative agent of alveolar echinococcosis, a severe zoonotic disease that may be fatal if untreated. A broad spectrum of mammalian species may be accidentally infected even in captivity. In April 2011, liver lesions due to E. multilocularis were observed during the necropsy of a captive-born nutria (Myocastor coypus) in a French wildlife park, leading to initiation of a study to survey the parasite's presence in the park. A comparable environmental contamination with fox's feces infected by E. multilocularis was reported inside (17.8%) and outside (20.6%) the park. E. multilocularis worms were found in the intestines of three of the five roaming foxes shot in the park. Coprological analyses of potential definitive hosts in captivity (fox, lynx, wildcat, genet, wolf, bear and raccoon) revealed infection in one Eurasian wolf. Voles trapped inside the park also had a high prevalence of 5.3%. After diagnosis of alveolar echinococcosis in a Lemur catta during necropsy, four other cases in L. catta were detected by a combination of ultrasound and serology. These animals were treated twice daily with albendazole. The systematic massive metacestode development and numerous protoscoleces in L. catta confirmed their particular sensitivity to E. multilocularis infection. The autochthonous origin of the infection in all the captive animals infected was genetically confirmed by EmsB microsatellite analysis. Preventive measures were implemented to avoid the presence of roaming foxes, contact with potential definitive hosts and contaminated food sources for potential intermediate hosts.
Domaines
SantéFormat du dépôt | Notice |
---|---|
Type de dépôt | Article dans une revue |
Titre |
en
Surveillance and management of Echinococcus multilocularis in a wildlife park.
|
Résumé |
en
The fox tapeworm Echinococcus multilocularis is the causative agent of alveolar echinococcosis, a severe zoonotic disease that may be fatal if untreated. A broad spectrum of mammalian species may be accidentally infected even in captivity. In April 2011, liver lesions due to E. multilocularis were observed during the necropsy of a captive-born nutria (Myocastor coypus) in a French wildlife park, leading to initiation of a study to survey the parasite's presence in the park. A comparable environmental contamination with fox's feces infected by E. multilocularis was reported inside (17.8%) and outside (20.6%) the park. E. multilocularis worms were found in the intestines of three of the five roaming foxes shot in the park. Coprological analyses of potential definitive hosts in captivity (fox, lynx, wildcat, genet, wolf, bear and raccoon) revealed infection in one Eurasian wolf. Voles trapped inside the park also had a high prevalence of 5.3%. After diagnosis of alveolar echinococcosis in a Lemur catta during necropsy, four other cases in L. catta were detected by a combination of ultrasound and serology. These animals were treated twice daily with albendazole. The systematic massive metacestode development and numerous protoscoleces in L. catta confirmed their particular sensitivity to E. multilocularis infection. The autochthonous origin of the infection in all the captive animals infected was genetically confirmed by EmsB microsatellite analysis. Preventive measures were implemented to avoid the presence of roaming foxes, contact with potential definitive hosts and contaminated food sources for potential intermediate hosts.
|
Auteur(s) |
Gérald Umhang
1
, Jennifer Lahoreau
, Vanessa Hormaz
, Jean-Marc Boucher
2
, Amandine Guenon
, Damien Montange
3
, Frédéric Grenouillet
3
, Franck Boue
1
ANSES -
Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail
( 301715 )
- 14 rue Pierre et Marie Curie
94701 MAISONS-ALFORT Cedex
- France
2
LGP2 -
Laboratoire Génie des procédés papetiers
( 703 )
- 461 Rue de la Papeterie - 38402 ST MARTIN D'HERES CEDEX
- France
3
LCE -
Laboratoire Chrono-environnement (UMR 6249)
( 57629 )
- 16, route de Gray - 25030 Besançon Cedex
- France
|
Langue du document |
Anglais
|
Nom de la revue |
|
Vulgarisation |
Non
|
Comité de lecture |
Oui
|
Audience |
Internationale
|
Date de publication |
2016-05-31
|
Volume |
65
|
Numéro |
3
|
Page/Identifiant |
245-50
|
Domaine(s) |
|
Mots-clés (Mesh) |
|
Pubmed Id | 26780546 |
Loading...