Longitudinal and circumferential mechanical behavior of human cerebral artery
Résumé
The prevalence of unruptured intracranial
aneurysms in the general population, as reported
by a recent review [Wardlaw, 2000], ranges
between 3% and 6.6%. However, the incidence
of ruptured aneurysms is low, with
approximately 0.5% per year, suggesting that
very few aneurysms rupture. Clearly, new
patient-specific indexes predicting aneurysm
risk of rupture should be proposed, in order to
guide therapeutic decision for unruptured
aneurysm.
Previously, we showed that aneurismal
pulsatility might be a relevant patient-specific
predictor of aneurysm risk of rupture [Sanchez,
2013], as the pulsability showed to provide
information on the degradation of the
mechanical properties of ruptured aneurism
tissue. However, the biomechanical properties
of healthy arteries of circle of Willis are poorly
reported. In this study, we attempted to identify
the biomechanical behavior of healthy
intracranial artery taken from autopsied
subjects.
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