The Bay of Quiberon (NW France), which is protected by the Quiberon Peninsula, provides well-preserved sedimentary archives for high-resolution reconstruction of Holocene climate variability. Very-high-resolution seismic profiles were obtained from two Seistec boomer seismic campaigns conducted in the bay. The seismic surveys reveal the deposition of five distinct sedimentary units. This succession is correlated with radiocarbon-dated sediments sampled in a long CASQ core (MD08-3204CQ). The analysis of the sediments shows significant changes in grain size, indicating a complex series of palaeo-climate events dated at 8800, 8600, 4270, 3860, 2470 and 1060 cal. yr BP. These may be correlated with millennial timescale climate variability corresponding to the phases of Holocene rapid climate changes (RCCs), associated with negative North Atlantic Oscillation (NAO) index and usually characterized by weaker winter storms. On the contrary, periods between RCCs are characterized by the predominance of westerly winds and stormy conditions for Brittany (i.e. positive NAO). However, only storm events occurring during the RCCs have been preserved in the Bay of Quiberon. This paper aims to reconstruct the Holocene sedimentary infill of the bay, highlighting the role of episodic acceleration phases of the sea-level rise on the preservation of sedimentary archives. Thus, the Bay of Quiberon provides substantially a complete sedimentation record of the last 10,000 years characterized by a series of complex palaeo-environmental changes.