Ion-atom collision cross-sections and transport coefficients are computed from several He2+ interaction potentials. Differential and integral momentum transfer cross-sections are obtained with a close-coupling quantum method using several literature interaction potentials. These collision cross-sections are used in an optimized Monte Carlo code to calculate the ion transport coefficients over a wide range of reduced electric field considering first the scattering anisotropy by using a differential cross-section and then an isotropic scattering approximation based on momentum transfer cross-section. Reduced mobilities are compared with available experimental data. This allows us to segregate accurate potentials which provide reduced mobilities falling within experimental error bars