Miniemulsion Polymerizations Using Static Mixers: Towards High Biocompatible Hydrophobe Contents
Résumé
Simple static mixers have been used as homogenization devices to perform polymerizable miniemulsion dispersions with negligible heat generation from mixtures containing vinyl acetate as the monomer and high amounts of biocompatible viscous oils (Miglyol and vitamin E acetate) as the hydrophobic components. A triblock nonionic copolymer was used as surfactant. The size of the initial droplets was in the 100-300nm range, increasing with the amount of the hydrophobe oil. These droplets have successfully been polymerized by using lauroyl peroxide or H2O2/ascorbic acid as initiators in order to get non-charged primary radicals. Stable nanoparticles with sizes around 300nm have been obtained that display colloidal stabilization at 4 and 25 degrees C upon a long storage time.