Since 2005, when BCI research activities started in our lab -- dealing with classification methods for the P300 Speller [1] -- we have mostly focused our attention on the development of palliative communication interfaces. Like in many labs our BCIs are based on EEG signal analysis, as much from the experimental point of view as from the scientific one. First, we will present the experimental goals of our group in terms of palliation of motor handicap. Then, we will present our scientific contribution to the development of BCI interfaces. These studies have been started thanks to several partners involved in different projects that we will finally clarify.