Multi-residue analysis of steroids at sub-ng/L levels in surface and ground-waters using liquid chromatography coupled to tandem mass spectrometry. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Chromatography A Année : 2008

Multi-residue analysis of steroids at sub-ng/L levels in surface and ground-waters using liquid chromatography coupled to tandem mass spectrometry.

Résumé

Most analytical methodologies currently available for the determination of steroids in water only identify a few representative compounds (mainly estrogens). In this context, a multi-residue methodology based on liquid chromatography-tandem mass spectrometry was developed for the determination of 26 steroids including natural and synthetic estrogens, progestagens and androgens. The method described involves limited sample preparation as it includes a filtration followed by a single solid-phase extraction step using a C18 cartridge. The analytical procedure allows the determination of the target analytes in the lower ng/L range, with recoveries above 80%. The methodology was successfully applied to the analysis of steroids in several surface and ground-waters. In all the waters, estrogens, androgens and/or progestagens were determined.

Dates et versions

hal-00509283 , version 1 (11-08-2010)

Identifiants

Citer

Emmanuelle Vulliet, Laure Wiest, Robert Baudot, Marie-Florence Grenier-Loustalot. Multi-residue analysis of steroids at sub-ng/L levels in surface and ground-waters using liquid chromatography coupled to tandem mass spectrometry.. Journal of Chromatography A, 2008, 1210 (1), pp.84-91. ⟨10.1016/j.chroma.2008.09.034⟩. ⟨hal-00509283⟩

Collections

CNRS SCA
33 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More