New methods for the dynamic analysis of tuned and mistuned bladed disks are presented. A new technique for disk substructuring using parameterized superelements is first described. It allows individual blade mistuning to be taken into account as slight variations in the reduced stiffness matrix of the bladed sectors or as shifts in fixed blade frequencies. A parametric multi-model reduction approach is then introduced to allow predictions of the evolution of vibration characteristics with respect to the rotation speed. Using prestressed solutions at three rotations speeds, this method allows a very accurate reanalysis of modes and forced responses of mistuned disks at all intermediate speeds