The dissertation is based on studies conducted in collaboration with the French Adhesion Society (Société Française de l’Adhésion), its members, and discussions during scientific events. It aims to present a chronological overview of adhesion and bonding, focusing primarily on polymers used as adhesives. The interdisciplinary nature of the research is highlighted, with a particular emphasis on epoxide-amine/metal systems. Interfaces, including interphases, between different materials are the main focus, analyzed through both post-mortem and in situ techniques such as mixing calorimetry. Collaboration with various institutions and experts has allowed for the development of analytical and digital methods to study these interfaces comprehensively. The research extends to various multi-material systems beyond epoxide-amine/metal, including ice on coated aluminum alloy, paints on different substrates, and hydroxyapatite coatings on titanium-based alloys. Future research directions include biomaterials, with a focus on applying knowledge gained from previous studies to dental and orthopedic applications. Collaboration with other experts and institutions is emphasized, with a keen interest in advancing analysis techniques like Raman spectroscopy and SEM-FIB. The researcher also expresses a commitment to open science principles, aiming to promote collaboration, open-source tools, and ethical considerations in research practices.