Locus-specific chromatin isolation
Résumé
Identifying factors bound to specific genomic loci in an unbiased manner is the holy grail of chromatin research, because it would provide an ultimate description of locus function. In this Comment, we explain why purifying a single locus represents a major technical challenge and provide recommendations for achieving this goal.
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Est complété par 10.1038/s41580-020-0222-3 Autre Vermeulen, M., & Déjardin, J. (2020). Publisher Correction: Locus-specific chromatin isolation. Nature Reviews Molecular Cell Biology, 21(5), 300–300. https://doi.org/10.1038/s41580-020-0222-3
Correction