Article Dans Une Revue Lab on a Chip Année : 2025

Light-based 3D printing and post-treatments of moulds for PDMS soft lithography

Résumé

Polydimethylsiloxane (PDMS) chips are still the workhorses of academic microfluidics. Their production requires the fabrication of moulds, commonly produced using clean-room technologies. Light-based 3D printing and in particular, vat photopolymerization, material jetting and two-photon polymerization are rising techniques for the fabrication of moulds for PDMS replication, thanks to their accessibility, fast prototyping time, and improving resolution. Here, we are first reviewing the possibility opened by 3D printing for soft lithography, with a focus on mould designs. Then, inhibition of PDMS curing by photosensitive resins will be discussed as the main technical hurdle of 3D printed moulds. Fortunately, mould post-treatments are efficient solutions to eliminate this curing inhibition, which we gathered in a large database of post-treatment protocols from the literature.

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Cite 10.5281/zenodo.14966980 Jeu de données Venzac, B. (2025). Post-treatment for 3D printed moulds (Version 1.0.1) [Data set]. Zenodo. https://doi.org/10.5281/ZENODO.14966980

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hal-05381311 , version 1 (25-11-2025)

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Bastien Venzac. Light-based 3D printing and post-treatments of moulds for PDMS soft lithography. Lab on a Chip, 2025, 25 (9), pp.2129-2147. ⟨10.1039/d4lc00836g⟩. ⟨hal-05381311⟩
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