Article Dans Une Revue Chemical Communications Année : 2019

Use of pyridazinediones as extracellular cleavable linkers through reversible cysteine conjugation

Calise Bahou
Richard Spears
Abil Aliev
  • Fonction : Auteur
Marcos Fernandez
Faiza Javaid
Peter Szijj
James Baker
Vijay Chudasama

Résumé

Herein we report the potential use of pyridazinediones as novel extracellular cleavable linkers in the context of protein bioconjugates.

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Dates et versions

hal-05324957 , version 1 (21-10-2025)

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Calise Bahou, Richard Spears, Abil Aliev, Antoine Maruani, Marcos Fernandez, et al.. Use of pyridazinediones as extracellular cleavable linkers through reversible cysteine conjugation. Chemical Communications, 2019, 55 (98), pp.14829-14832. ⟨10.1039/c9cc08362f⟩. ⟨hal-05324957⟩
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