Article Dans Une Revue Asian Journal of Research in Infectious Diseases Année : 2025

Prognostic Assessment of Tetanus in Cases of Bacterial Entry Portal Identified, Bamako, Mali

Résumé

Objective: To determine the main types of tetanogenic bacterial portals of entry and assess their involvement in the prognostic and evolutionary factors of tetanus. Methodology: We carried out a descriptive and analytical cross-sectional study with retrospective data collection at Point-G University Hospital over a period of 22 years. Our study population was made up of tetanus patients whose bacterial portals of entry were sought and found or not found upon admission. Results: The hospital prevalence of tetanus was 5% of admissions. The portal of entry (POE) was found in 217 cases (84.10%). The most common bacterial portals of entry found (BPOEF) were skin and mucosal wounds (65.4%), open fractures (10.6%), skin lesions (7.8%) and deep wounds (7.4%). The most common anatomical sites were the pelvic limbs (62.2%), thoracic limbs (26.3%), head (5.5%) and uterus (2%). The comorbidities associated with the death were dominated by hypertension (50%), malaria (28.6%), and one case of epilepsy, with (p=0.96) compared to the survivors with comorbidities. The POEs as variable dependent of the Dakar score were: 22 POEs due to open fractures, 6 POEs following surgery, 4 POEs after IM injections, 4 POEs due to uterine invasion, and 2 POEs following burns. Dakar scores 2 and 3 were predominantly recorded in cases of BPOEF respectively 48.8% and 31.8%. Specifically, 41.5% of deaths were recorded in patients with BPOEF versus patients BPOE-NF (46.3%) with p=0.77. The mortality in the group with POEs as variable dependent of tetanus risk factors was 42.1% versus 42.5% in the group with POEs as variable independent of risk factors. The Dakar poor prognosis scores were higher in patients whose BPOEF, with a statistically significant difference (p=0.043). Conclusion: Tetanus continues to be seen despite the availability of effective preventative measures. Given the multitude of comorbidities and the associated significant mortality rate, there would need to be a review of the prognostic factors for tetanus in healthcare settings.

Fichier non déposé

Dates et versions

hal-05307101 , version 1 (10-10-2025)

Identifiants

  • HAL Id : hal-05307101 , version 1

Citer

Traoré Abdoulaye Mamadou, Dabo Garan, Dollo Ibrahim, Dara Charles, Cissé Hamsatou, et al.. Prognostic Assessment of Tetanus in Cases of Bacterial Entry Portal Identified, Bamako, Mali. Asian Journal of Research in Infectious Diseases, 2025, 16 (10), pp.21-28. ⟨hal-05307101⟩
13 Consultations
0 Téléchargements

Partager

  • More