How Does Body Composition Influence Left Ventricular Architecture?
Résumé
This study evaluated the relationship between body composition and left ventricular morphology in young healthy non-obese males and females. Left ventricular morphology may be affected by alteration in body composition. Various cardiac and non-cardiac diseases are known to alter left ventricular morphology. Echocardiography can noninvasively find this alteration. The study was conducted after being approved by the institutional ethics committee, GMC, Nagpur. This was the cross sectional study done on 100 (51 male & 49 female) physical education college student in the age group of 17 to 22 years. Left ventricular structure was analyzed by 2-D and M-mode echocardiography. Body composition was analyzed using bioelectrical impedance analysis. Pearson correlation analysis and stepwise multiple regression analysis between body composition parameters and left ventricular structure was done using SPSS16 software. In males, end systolic left ventricular posterior wall thickness (LVPWs) showed significant correlation with weight (r=0.348, p<0.05), BMI (r=0.293, p<0.05), BSA (r=0.314, p<0.05) and fat free mass (r=0.284, p<0.05). BMI showed significant correlation with end systolic left ventricular Internal diameter (LVIDs) (r=0.309, p<0.05), end diastolic Inter ventricular septal thickness (IVSd) (r=0.299, p<0.05) and left ventricular mass (r=0.370, p<0.01). End diastolic Inter ventricular septal thickness (IVSd) also showed significant correlation with weight. (r=0.296, p<0.05) No significant correlation was seen in female subjects. This study showed that the body composition influences some cardiac structural parameters in adult male subjects. Indexation of left ventricular morphology parameter by fat free mass may not be required in persons with the normal BMI without any risk factor. Further studies are recommended with the large sample size.