An original approach for multiscale modeling of the skeletal muscle
Résumé
Finite element (FE) models are increasingly used to analyze the effect of components at different scales on the overall mechanical response of the skeletal muscle [1]. The most critical points lie in modeling the transition from one anatomical scale to the others. We propose to use periodic Representative Volume Elements (RVE) to integrate parameters related to muscle fiber type distribution, geometric and mechanical characteristics. We developed an original approach based on 3D periodic RVE generation for the multiscale FE modeling of the skeletal muscle. By including custom geometrical features (such as component distributions) and material properties (including a smooth transition layer), this model could be used for multiscale, multi-component analysis of different muscle phenotypes.
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