Communication Dans Un Congrès Année : 2025

Respiration Can Trigger Cerebrovascular Reactivity: A New Method to Quantify Respiratory-Driven CVR Using Real-time phase contrast MRI

Résumé

Motivation: Quantifying cerebrovascular reactivity (CVR) is key for diagnosing and understanding neurological diseases. However, measuring respiratory-driven CVR is challenging due to the difficulty in separating cardiac effects from CVR modulation. Goal(s): Propose a novel approach to accurately quantify respiratory-driven CVR. Approach: Using real-time phase-contrast sequences and respiratory signals to quantify respiratory-driven CVR by analysing the flow ratio (Ratio-Q) between the internal and external carotid arteries. Results: Sustained deep breathing increases cerebrovascular resistance causing a 20% reduction in average carotid artery flow and Ratio-Q. CVR also regulates cerebrovascular resistance at the respiratory frequency, stabilizing cerebral blood flow fluctuations. Impact: This study introduces a new, effective method for measuring respiratory-driven CVR, comparing results across two different breathing modes. It provides crucial methodological support and reference data for clinical and physiological research.

Fichier principal
Vignette du fichier
0278_RESP_CVR.pdf (1.6 Mo) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)
Licence

Dates et versions

hal-05092743 , version 1 (02-06-2025)
hal-05092743 , version 2 (12-06-2025)

Licence

Identifiants

  • HAL Id : hal-05092743 , version 1

Citer

Pan Liu, Qiuting Wen, K. P. Owashi, Olivier Balédent. Respiration Can Trigger Cerebrovascular Reactivity: A New Method to Quantify Respiratory-Driven CVR Using Real-time phase contrast MRI. ISMRM 2025-International Society for Magnetic Resonance in Medicine, Proc. Intl. Soc. Mag. Reson. Med., May 2025, Honolulu (Hawai'i), United States. ⟨hal-05092743v1⟩
338 Consultations
236 Téléchargements

Partager

  • More