Article Dans Une Revue Chemistry - A European Journal Année : 2016

Biologically Active Heteroglycoclusters Constructed on a Pillar[5]arene‐Containing [2]Rotaxane Scaffold

Résumé

A synthetic approach combining recent concepts for the preparation of multifunctional nanomolecules (click chemistry on multifunctional scaffolds) with supramolecular chemistry (self‐assembly to prepare rotaxanes) gave easy access to a large variety of sophisticated [2]rotaxane heteroglycoclusters. Specifically, compounds combining galactose and fucose have been prepared to target the two bacterial lectins (LecA and LecB) from the opportunistic pathogen Pseudomonas aeruginosa .

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hal-05017678 , version 1 (02-04-2025)

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Stéphane P Vincent, Kevin Buffet, Iwona Nierengarten, Anne Imberty, Jean-Franco̧is Nierengarten. Biologically Active Heteroglycoclusters Constructed on a Pillar[5]arene‐Containing [2]Rotaxane Scaffold. Chemistry - A European Journal, 2016, 22 (1), pp.88 - 92. ⟨10.1002/chem.201504110⟩. ⟨hal-05017678⟩
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