Article Dans Une Revue Cancer Chemotherapy and Pharmacology Année : 2006

Dexamethasone as a probe for CYP3A4 metabolism: evidence of gender effect

Résumé

A study was conducted to evaluate prospectively the correlation between docetaxel clearance and pharmacokinetics of dexamethasone previously obtained in 21 patients.

Dexamethasone may be used to predict docetaxel clearances in females, but not in males.

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Dates et versions

hal-04970336 , version 1 (27-02-2025)

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F. Puisset, E. Chatelut, A. Sparreboom, J.-P. Delord, D. Berchery, et al.. Dexamethasone as a probe for CYP3A4 metabolism: evidence of gender effect. Cancer Chemotherapy and Pharmacology, 2006, 60 (2), pp.305-308. ⟨10.1007/s00280-006-0385-4⟩. ⟨hal-04970336⟩
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