Article Dans Une Revue (Data Paper) IJID Regions Année : 2022

Severe acute respiratory syndrome coronavirus 2 antibody seroprevalence in Lebanon: a population-based cross-sectional study

Ahmad Mahdi
  • Fonction : Auteur
Georges Khazen
  • Fonction : Auteur
Nivine Aziz
  • Fonction : Auteur
Jonathan Mina
  • Fonction : Auteur
Aram Papazian
  • Fonction : Auteur
Leonardo Daou
Jana Ahmar
  • Fonction : Auteur
Nour Assaf
  • Fonction : Auteur
Anjy Abdulkhalek
  • Fonction : Auteur
Hussein Farhat
  • Fonction : Auteur
Jacques Mokhbat
  • Fonction : Auteur
Anna Farra
Rola Husni
  • Fonction : Auteur
  • PersonId : 1499390

Résumé

Objectives: The World Health Organization has promoted the use of serological testing as a rapid and accurate technique for the detection of immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In Lebanon, a better understanding of the immune response against SARS-CoV-2 is needed to develop effective measures for prevention and to plan an appropriate national vaccination program. This study aimed to measure the immunity status in Lebanon. Methods: In this cross-sectional study, the population comprised male and female Lebanese and non-Lebanese residents of Lebanon between the ages 15 and 75. The exclusion criteria included: same household, symptomatic individuals, and extremes of age ( < 15 and > 75). Representative testing for SARS-CoV-2 antibodies (anti-SARS-CoV-2 electrochemiluminescence immunoassay/ECLIA) was used to assess the prevalence of SARS-CoV-2 infection in Lebanon. Results: In total, 13 755 participants were recruited over a 6-month period. Of these, 3168 (23.03%) individuals tested positive for anti-SARS-CoV-2, with levels of positivity varying among districts. A higher level of seropositivity was detected in the female participants. Conclusion: Seroprevalence against SARS-CoV-2 varied within Lebanon, but was comparable to the levels reported in the MENA region at the time of the study. The seroprevalence documented in this study represents a level of immunity that is not protective at the national level.

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hal-04920359 , version 1 (30-01-2025)

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Ahmad Mahdi, Georges Khazen, Nivine Aziz, Jonathan Mina, Aram Papazian, et al.. Severe acute respiratory syndrome coronavirus 2 antibody seroprevalence in Lebanon: a population-based cross-sectional study. IJID Regions, 2022, 2, pp.184 - 190. ⟨10.1016/j.ijregi.2022.01.011⟩. ⟨hal-04920359⟩
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