Article Dans Une Revue Tetrahedron Année : 1992

Reaction of phenylacetate enolates with γ- bromo α,β-unsaturated derivatives: diastereo-and enantioselective allylic substitution

Résumé

The reaction of Li t.butyl phenylacetate enolate with γ-bromo-α,β-unsaturated esters 1a,b is regio-and stereoselective. Asymmetric synthesis can be performed with a chiral ester 1d. With amide 1c, the regio-and stereoselectivity are poor.

Dates et versions

hal-04899095 , version 1 (20-01-2025)

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Citer

Anne-Françoise Sevin, Jacqueline Seyden-Penne, Kamal Boubekeur. Reaction of phenylacetate enolates with γ- bromo α,β-unsaturated derivatives: diastereo-and enantioselective allylic substitution. Tetrahedron, 1992, 48 (30), pp.6253-6264. ⟨10.1016/S0040-4020(01)88217-X⟩. ⟨hal-04899095⟩
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